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NMIN Publication Database

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The database below lists publications emerging from  NMIN-supported research projects.

The database can be searched or sorted by any field. When searching by author, use last name only.

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AuthorsTitleJournalYear
Alexander Dhaliwal and Gang Zheng

Improving accessibility of EPR-insensitive tumor phenotypes using EPR-adaptive strategies: Designing a new perspective in nanomedicine delivery

Theranostics

2019
Kara M. Harmatys, Marta Overchuk and Gang Zheng

Rational Design of Photosynthesis-Inspired Nanomedicines

Accounts of Chemical Research

2019
Keegan Guidolin, Gang Zheng

Nanomedicines Lost in Translation

ACS Nano

2019
Marta Overchuk, , Mark Zheng, Maneesha A. Rajora, Danielle M. Charron, Juan Chen, and Gang Zheng

Tailoring Porphyrin Conjugation for Nanoassambly-Driven Phototheranostic Properties

ACS Nano

2019
Joseph M. Keca, Gang Zheng

Texaphyrin: From Molecule to Nanoparticle

Coordination Chemistry Reviews

2019
Joseph M Keca, Michael S Valic, Miffy H Y Cheng, Wenlei Jiang, Marta Overchuk, Juan Chen, Gang Zheng

Mix and Match Metallo-nanotexaphyrin for Customizable Biomedical Imaging

Advanced Healthcare Materials

2019
Chen KTJ, Anantha M, Leung AWY, Kulkarni JA, Militao GGC, Wehbe M, Sutherland B, Cullis PR, Bally MB.

Characterization of a Liposomal copper(II)-quercetin Formulation Suitable for Parenteral Use

Drug Delivery and Translational Resesearch

2019
Akinc A, Maier MA, Manoharan M, Fitzgerald K, Jayaraman M, Barros S, Ansell S, Du X, Hope MJ, Madden TD, Mui BL, Semple SC, Tam YK, Ciufolini M, Witzigmann D, Kulkarni JA, van der Meel R, Cullis PR.

The Onpattro Story and the Clinical Translation of Nanomedicines Containing Nucleic Acid-Based Drugs

Nature Nanotechnology

2019
Witzigmann D, Kulkarni JA, Leung J, Chen S, Cullis PR, van der Meel R.

Lipid nanoparticle technology for therapeutic gene regulation in the liver

Advanced Drug Delivery Reviews

2020
Francia V, Schiffelers RM, Cullis PR, Witzigmann D.

The Biomolecular Corona of Lipid Nanoparticles for Gene Therapy

Bioconjugate Chemistry

2020
Kulkarni JA, Thomson SB, Zaifman J, Leung J, Wagner PK, Hill A, Yi Y, Tam C, Cullis PR, Petkaubc TL, Leavitt BR.

Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles

Nanoscale

2020
Strilchuk AW, Meixner SC, Leung J, Safikhan N, Kulkarni JA, Russell HM, van der Meel R, Sutherland MR, Owens AP, Palumbo J, Conway EM, Pryzdial ELG, Cullis P, Kastrup CJ.

Sustained Depletion of FXIII-A by Inducing Acquired FXIII-B Deficiency

Blood

2020
Hartjes TA, Slotman JA, Vredenbregt MS, Dits N, van der Meel R, Djuivesz D, Kulkarni JA, French PJ, van Cappellen QA, Schiffelers RM, Houtsmuller AB, Jenster GW, van Royen M.

EVQuant; high-throughput quantification and characterization of extracellular vesicle (sub)populations

bioRxiv

2020
Valic M, Halim M, Schimmer P, Zheng G.

Guidelines for the experimental design of pharmacokinetic studies with nanomaterials in preclinical animal models

Journal Controlled Release

2020
Poon W, Kingston B, Ouyang B, Ngo W.

A framework for designing delivery systems

Nature Nanotechnology

2020
Malik G, Zhou Y.

Innate Immune Sensing of Influenza A Virus

Viruses

2020
Ouyang B, Poon W, Zhang Y-N, Lin ZP, Kingston BR, Tavares AJ, Zhang Y, Chen J, Valic MS, Syed AM, MacMillan P, Couture-Senécal J, Zheng G, Chan WCW.

The dose threshold for nanoparticle tumour delivery

Nature Materials

2020
Henrickson A, Kulkarni JA, Zaifman J, Gorbet G, Cullis PR, Demeler B.

Density Matching – Multi-Wavelength Analytical Ultracentrifugation to Measure Drug Loading of Lipid Nanoparticle Formulations

ACS Nano

2020
Ul Ain Q, Campos EVR, Huynh A, Witzigmann D, Hedtrich S.

Gene Delivery to the Skin – How Far Have We Come?

Trends in Biotechnology

2020
Marta Overchuk, Martha P F Damen, Kara M Harmatys, Martin G Pomper, Juan Chen, Gang Zheng

Long-Circulating Prostate-Specific Membrane Antigen-Targeted NIR Phototheranostic Agent

Photochemistry and Photobiology

2020
Mazinani N, Strilchuk AW, Baylis JR, Hur WS, Jefferies WA, Kastrup CJ.

Bleeding is increased in amyloid precursor protein knockout mouse

Research and Practice in Thrombosis and Haemostasis

2020
Juang LJ, Mazinani N, Novakowski SK, Prowse ENP, Haulena M, Gailani D, Lavkulich L, Kastrup CJ.

Coagulation factor XII contributes to hemostasis when activated by soil in wounds

Blood Advances

2020
Hur WS, Juang LJ, Mazinani N, Munro L, Jefferies WA, Kastrup CJ.

Post-Translational Modifications of Platelet-Derived Amyloid Precursor Protein by Coagulation Factor XIII-A*

Biochemistry

2020
Muhanna N, Chan H, Townson J, Jin CS, Ding LL, Douglas C, Valic M, MacLaughlin CM, Chen J, Zheng G, Irish JC.

Photodynamic therapy enables tumor-specific ablation in preclinical models of thyroid cancer

Endocrine-Related Cancer

2020
Zhang Y, Wu JLY, Lazavorits J, Chan WCW.

An analysis of the binding function and structural organization of the protein corona

Journal of the American Chemical Society

2020
Sindhwani S, Syed AM, Ngai J, Kingston BR, Maiorino L, Rothschild J, MacMillan P, Zhang Y, Rajesh NU, Hoang T, Wu JLY, Wilhelm S, Zilman A, Gadde S , Sulaiman A, Ouyang B, Lin Z, Wang L, Egeblad M, Chan WCW.

The entry of nanoparticles into solid tumours

Nature Materials

2020
Hassan EM, Walker GC, Wang C, Zou S.

Anti-leukemia effect associated with down-regulated CD47 and up-regulated calreticulin by stimulated macrophages in co-culture

Cancer Immunology, Immunotherapy

2020
Roberts ME, Barvalia M, Silva JAFD, Cederberg RA, Chu W, Wong A, Tai DC, Chen S, Matos I, Priatel JJ, Cullis PR, Harder KW.

Deep Phenotyping by Mass Cytometry and Single-Cell RNA-Sequencing Reveals LYN-Regulated Signaling Profiles Underlying Monocyte Subset Heterogeneity and Lifespan

Circulation Research

2020
Tian X, Landreth S, Lu Y, Pandey K, Zhou Y.

A replication-defective influenza virus harboring H5 and H7 hemagglutinins provides protection against H5N1 and H7N9 infection in mice

Journal of Virology

2020
Landreth S, Lu Y, Pandey K, Zhou Y.

A replication-defective influenza virus vaccine confers complete protection against H7N9 viral infection in mice

Vaccines

2020
Matthews Q, Silva SJRD, Norouzi M, Pena LJ, Pardee K.

Adaptive, Diverse and De-centralized Diagnostics are Key to the Future of Outbreak Response

BMC Biology

2020
Carlaw TM, Zhang L-H, Ross CJD.

CRISPR/Cas9 Editing: Sparking Discussion on Safety in Light of the Need for New Therapeutics

Human Gene Therapy

2020
Hok Yan Cheng M, Mo Y, Zheng G.

Nano versus Molecular: Optical Imaging Approaches to Detect and Monitor Tumor Hypoxia

Advanced Healthcare Materials

2020
Terada T, Kulkarni JA, Huynh A, Yi Y, Tam C, Cullis P.

Protective effect of Edaravone against cationic lipid-mediated oxidative stress and apoptosis

Bulletins of the Pharmaceutical Society of Japan

2021
Terada T, Kulkarni JA, Huynh A, Chen S, van der Meel R, Yi Y, Tam C, Cullis PR.

Characterization of Lipid Nanoparticles Containing Ionizable Cationic Lipids Using Design-of-Experiment Approach

Langmuir

2021
Sindhwani S, Chan WCW.

Nanotechnology in modern medicine: Next steps towards clinical translation

Journal of Internal Medicine

2021
Denroche HC, Miard S, Sallé-Lefort S, Picard F, Verchere CB.

T cells accumulate in non-diabetic islets during ageing

Immunity and Ageing

2021
Sadat SMA, Paiva IM, Shire Z, Sanaee F, Morgan TDR, Paladino M, Karimi-Busheri F, Mani RS, Martin GR, Jirik FR, Hall DG, Weinfeld M, Lavasanifar A

A synthetically lethal nanomedicine delivering novel inhibitors of polynucleotide kinase 3′-phosphatase (PNKP) for targeted therapy of PTEN-deficient colorectal cancer

Journal of Controlled Release

2021
Chander N, Morstein J, Bolten JS, Shemet A, Cullis PR, Trauner D, Witzigmann D

Optimized Photoactivatable Lipid Nanoparticles Enable Red Light Triggered Drug Release

Small

2021
Tam A, Leclair P, Li LV, Yang CX, Li X, Witzigmann D, Kulkarni JA, Hackett T-L, Dorscheid DD, Singhera GK, Hogg JC, Cullis PR, Sin DD, Lim CJ

FAM13A as potential therapeutic target in modulating TGF-beta-induced airway tissue 1 remodeling in COPD

American Journal of Physiology-Lung Cellular and Molecular Physiology

2021
Alhussan A, Bromma K, Perez MM, Beckham W, Alexander AS, Howard PL, Chithrani DB

Docetaxel-Mediated Uptake and Retention of Gold Nanoparticles in Tumor Cells and in Cancer-Associated Fibroblasts

Cancers (Basel)

2021
Pauli G, Chao P-H, Qin Z, Böttger R, Lee SE, Li S-D

Liposomal Resiquimod for Enhanced Immunotherapy of Peritoneal Metastases of Colorectal Cancer

Pharmaceutics

2021
Leung J, Cau M, Kastrup CJ

Emerging gene therapies for enhancing the hemostatic potential of platelets

Transfusion

2021
Kamanzi A, Gu Y, Tahvildari R, Friedenberger Z, Zhu X, Berti R, Kurylowicz M, Witzigmann D, Kulkarni JA, Leung J, Andersson J, Dahlin A, Hook A, Sutton M, Cullis PR, Leslie S

Simultaneous, Single-Particle Measurements of Size and Loading Give Insights into the Structure of Drug-Delivery Nanoparticles

ACS Nano

2021
Sadat MA, Wuest M, Paiva IM, Munira S, Sarrami N, Sanaee F, Yang X, Paladino M, Binkhathlan Z, Karimi-Busheri F, Martin GR, Jirik FR, Murray D, Gamper AM, Hall DG, Weinfeld M, and Lavasanifar A

Nano-Delivery of a Novel Inhibitor of Polynucleotide Kinase/Phosphatase (PNKP) for Targeted Sensitization of Colorectal Cancer to Radiation-Induced DNA Damage

Frontiers in Oncology

2021
Alhussan, A.; Bromma, K.; Bozdogan, E. P.; Metcalfe, A.; Karasinska, J.; Beckham, W.; Alexander, A. S.; Renouf, D. J.; Schaeffer, D. F. and Chithrani, D. B

Investigation of Nano-Bio Interactions within a Pancreatic Tumor Microenvironment for the Advancement of Nanomedicine in Cancer Treatment

Current Oncology

2021
Miffy H. Y. Cheng, Marta Overchuk, Maneesha A. Rajora, Jenny W. H. Lou, Ying Chen, Martin G. Pomper, Juen Chen, and Gang Zheng

Targeted Theranostic 111In/Lu-Nanotexaphyrin for SPECT Imaging and Photodynamic Therapy

Molecular Pharmaceutics

2021
Jenny Lou, Masato Aragaki , Nicholas Bernards, Tomonari Kinoshita, Jessica Mo, Yamoto Motooka, Tsukasa Ishiwata, Alexander Gregor , Tess Chee, Zhenchian Chen, Juan Chen, Kichizo Kaga, Satoru Wakasa, Gang Zheng and Kazuhiro Yasufuku

Repeated porphyrin lipoprotein-based photodynamic therapy controls distant disease in mouse mesothelioma via the abscopal effect

Nanophotonics

2021
Keegan Guidolin , Lili Ding, Juan Chen, Brian C. Wilson and Gang Zheng

Porphyrin-lipid nanovesicles (Porphysome) are effective photosensitizers for photodynamic therapy

Nanophotonics

2021
Miffy. H. Y. Cheng, Alberto Cevallos, Maneesha A. Rajora and Gang Zheng

Fast, facile, base-free microwave-assisted metalation of bacteriochlorophylls and corresponding high yield synthesis of TOOKAD

Journal of Porphyrins and Phthalocyanines

2021
Marta Overchuk, Kara M Harmatys, Shrey Sindhwani, Maneesha A Rajora, Adam Koebel, Danielle M Charron, Abdullah M Syed, Juan Chen, Martin G Pomper, Brian C Wilson, Warren C W Chan, Gang Zheng

Subtherapeutic Photodynamic Priming Facilitates Tumor Nanomedicine Delivery and Overcomes Desmoplasia

Nano Letters

2021
Julian Vogler, Roland Bottger, Nojoud AL Fayez, Wunan Zhang, Zhu Qin, Lukas Hohenwarter, Po-Han Chao, Elham Rouhollahi, Nida Bilal, Naliangzi Chen, Brandon Lee, Christine Chen, Brayden Wilkinson, Timonthy Kieffer, Jayesh Kulkarni, Pieter Cullis, Dominik W

Altering the intra-liver distribution of phospholipid-free small unilamellar vesicles using temperature-dependent size-tunability

Journal of Controlled Release

2021
Roy van der Meel, Sam Chen, Josh Zaifman, Jayesh A. Kulkarni, Xu Ran S. Zhang, Ying K. Tam, Marcel B. Bally, Raymond M. Schiffelers, Marco A. Ciufolini, Pieter R. Cullis, and Yuen Yi C. Tam

Modular Lipid Nanoparticle Platform Technology for siRNA and Lipophilic Prodrug Delivery

Small

2021
Jayesh A. Kulkarni, Sam Chen, and Yuen Yi C. Tam

Scalable Production of Lipid Nanoparticles Containing Amphotericin B

Langmiur

2021
Kent T.J. Chen, Gardenia G.C. Militao, Malathi Anantha, Dominik Witzigmann, Ada W.Y. Leung, Marcel B. Bally

Development and characterization of a novel flavopiridol formulation for treatment of acute myeloid leukemia

Journal of Controlled Release

2021
Kent T.J. Chen, Gardenia G.C. Militao, Malathi Anantha, Dominik Witzigmann, Ada W.Y. Leung, Marcel B. Bally

Development and characterization of a novel flavopiridol formulation for treatment of acute myeloid leukemia

Journal of Controlled Release

2021
Cau MF, Strilchuk AW, Kastrup CJ.

Nanomedicines for hemorrhage control

Journal of Thrombosis and Haemostasis

2021
Lu Y, Landreth S, Liu G, Brownlie R, Gaba A, Gerdts V, Zhou Y.

Innate immunemodulator containing adjuvant formulated HA based vaccine protects mice from lethal infection of highly pathogenic avian influenza H5N1 virus

Vaccine

2021
Amalfitano E, Karlikow M, Norouzi M, Jaenes K, Cicek S, Masum F, Sadat Mousavi P, Guo Y, Tang L, Sydor A, Ma D, Pearson JD, Trcka D, Pinette M, Ambagala A, Babiuk S, Pickering B, Wrana J, Bremner R, Mazzulli T, Sinton D, Brumell JH, Green AA, Pardee K.

A Glucose Meter Interface for Point-of-Care Gene Circuit-based Diagnostics

Nature Communications

2021
Aibani, N., Patel, P., Buchanan, R., Strom, S., Wasan, K., Hancock, R.E.W., Gerdts, V., Wasan, E.K.

Assessing the In Vivo Effectiveness of Cationic Lipid Nanoparticles with a Triple Adjuvant for Intranasal Vaccination against the Respiratory Pathogen Bordetella pertussis

Molecular Pharmaceutics

2022
Han, O., Bromma, K., Palmerley, N., Monica, M., Alhussan, A., Howard, P., Beckam, W., Abraham, A., & Chithrani, B. D

Nanotechnology driven cancer chemoradiation: Exploiting the full potential of radiotherapy with a unique combination of gold nanoparticles and bleomycin

Current Oncology

2022
Roy Pattipeiluhu, Gabriela Arias-Alpizar, Genc Basha, Karen Y.T. Chan, Jeroen Bussmann, Thomas H. Sharp, Mohammad-Amin Moradi, Nico Sommerdijk, Edward N. Harris, Pieter R. Cullis, Alexander Kros, Dominik Witzigmann, Frederick Campbell

Anionic Lipid Nanoparticles Preferentially Deliver mRNA to the Hepatic Reticuloendothelial System

Advanced Materials

2022