Publication

A new special issue of the American Chemical Society journal Molecular Pharmaceutics highlights outstanding work related to contemporary nanomedicine research in Canada. The issue, “Tiny Things, Huge Impact: Nanomedicine in Canada,”  was edited by NMIN researchers Dr. Shyh-Dar Li, Ellen Wasan, Marcel Bally, and Sarah Hedtrich, who contribute an editorial summarizing the… Read More »Canadian nanomedicines in the spotlight: Molecular Pharmaceutics

The research in Small featured below is from the laboratories of Drs. Dominik Witzigmann (top center) and Pieter Cullis (bottom left) at UBC and Dr. Dirk Trauner (bottom right) at New York University. The lead authors are Nisha Chander (top right) and Dr. Johannes Morstein (top left). NMIN-supported research has… Read More »Lipid nanoparticles in COPD treatment & for light-triggered anticancer drug release: two NMIN-supported papers

Dr. Cullis stepping down as Scientific Director to pursue commercialization opportunities NMIN’s founding Scientific Director, Dr. Pieter Cullis, seizes yet another new opportunity. Over his celebrated career, he has spearheaded numerous innovations and created a range of new business opportunities for Canadians through his intrepid entrepreneurialism. Most recently, his aptitude… Read More »NMIN’s Scientific Director changes course

In a January 15, 2021 seminar organized by the Life Sciences Institute of the University of British Columbia, NMIN’s Scientific Director Dr. Pieter Cullis shared a first-hand account of the 40-year scientific journey that culminated in the lipid nanoparticle (LNP) delivery system underpinning the Pfizer/BioNTech vaccine against COVID-19. Watch the… Read More »NMIN’s Scientific Director tells the story of the LNP delivery system behind Pfizer’s COVID-19 vaccine

In a review article published today in Advanced Healthcare Materials, NMIN trainees Dr. Miffy Hok Yan Cheng and Yulin Mo, together with NMIN researcher Dr. Gang Zheng, survey the latest nano and molecular developments in optical imaging approaches for detecting and monitoring hypoxia in solid tumours. “Hypoxia is a hallmark… Read More »Nano versus Molecular: Optical Imaging Approaches to Detect and Monitor Tumor Hypoxia – a review by NMIN researcher & trainees

Three reviews by NMIN researchers – Drs Pieter Cullis, Shana Kelley, Dominik Witzigmann, and Gang Zheng – have been honoured with inclusion in 30th anniversary issues of the journal Bioconjugate Chemistry. “Throughout 2020, Bioconjugate Chemistry is holding a year-round celebration with a special group of invited review authors,” comments NMIN… Read More »NMIN researchers featured in 30^th anniversary issues of Bioconjugate Chemistry

NMIN researcher Dr. Sarah Hedtrich, her team including NanoCore`s Operational Lead Dr. Dominik Witzigmann, discuss the status of gene therapies as tools for treating skin disease in a review article published in Trends in Biotechnology. “In this review, we discuss current approaches, successes, and failures of cutaneous gene therapy and… Read More »NMIN researchers discuss gene therapies for skin disease

NMIN researchers and colleagues have discovered a nanoparticle threshold dose that improves nanoparticle delivery and therapy for solid tumours. Published in Nature Materials, the study emerged from Dr. Warren Chan‘s Integrated Nanotechnology & Biomedical Sciences Laboratory at the University of Toronto, with NMIN researchers Drs. Chan and Gang Zheng as… Read More »NMIN researchers discover dose threshold for nanoparticle tumour delivery

In a new review article in Human Gene Therapy, NMIN researcher Dr. Colin Ross and NMIN HQP Tiffany Carlaw and Lin-Hua Zhang provide an overview of the current state of CRISPR/Cas9 base and prime editing technologies. “Therapeutic base editing is one form of genome engineering that has gained much interest… Read More »NMIN researchers discuss the current state of CRISPR/Cas9 editing