Abstracts/Posters Database
Vancouver Nanomedicine Day 2020

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No.NameTitlePosterTheme/Program
1 Albert Kamanzi

Single-particle imaging of lipid nanoparticles for drug delivery applications

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Targeted drug delivery
Gene therapy
Microfluidics
2

Alice Li

Silencing of Growth Hormone Receptor by siRNA Ameliorated Disease in a Preclinical Rat Model of Acromegaly

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Gene therapy
3

Amanda Santos Palma

The influence of lysozyme in the structural features of cubosomes: a potential drug delivery system

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Targeted drug delivery
4

Amy Wong Strilchuk

Transient gene therapy to decrease the stability of thrombi for coagulopathy and thrombosis

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Gene therapy
5

Ana Silva

Pessaries with progesterone-loaded nanostructured lipid carriers (NLC) for prolonged release

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Nanomedicine
6

Colin Blackadar

Preparation of Heat-Denatured Macroaggregated Albumin for Biomedical Applications using a Microfluidics Platform

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Targeted drug delivery
Microfluidics
7

Cynthia Shaheen

Single Molecule Imaging of DNA Structure: CLiC Microscopy Powers Mechanistic Insights for Drug Development

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Diagnostics
Microfluidics
Drug Development & Testing Technology
8

Enling Chang

Combination of photodynamic therapy and chemotherapy for cancer treatment by using paclitaxel loaded porphyrin-shelled nanoemulsions

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Targeted drug delivery
Cancer treatment
9

Eva Mueller

Cationic, anionic, and amphoteric dual pH/temperature-responsive degradable microgels via self-assembly of functionalized oligomeric precursor polymers

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Targeted drug delivery
10

Fernando Freitas de Lima

Development and Characterization of Lipid Nanocapsules with Attalea Phalerata Pulp Oil

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Bioactive compounds
11

Forugh Sanaee

Pharmacokinetics of Nano versus Conventional Formulations of A83B4C63, a Novel Inhibitor of DNA Repair in Rat

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Targeted drug delivery
Cancer treatment
12

Jessalyn Baljon

A Nanocarrier Platform for Enhancing Immune Responses to Neoantigen-Targeted Cancer Vaccines

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Targeted drug delivery
Cancer treatment
13

Karin Torres-Obreque

PEGylation the key for increased thermostability of biopharmaceuticals: crisantaspase case-study

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Cancer treatment
14

Laxmi Swetha

Docetaxel and disulfiram loaded tumor extracellular pH-responsive nanocarrier for targeting cancer stem cells

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Targeted drug delivery
Microfluidics
Cancer treatment
15

Letizia Nicoletti

Novel lipoplexes for efficient microRNA delivery to human cardiac fibroblasts

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Gene therapy
16

Mahmoud Younis

Manipulation of the Composition and Physico-chemical Properties of Combo Lipid Nanoparticles for Highly-selective Chemo-gene Therapy of Hepatocellular Carcinoma In Vivo

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Targeted drug delivery
Gene therapy
Microfluidics
Cancer treatment
17

Maria Poley

Chemotherapeutic Nanoparticles Accumulate in the Female Reproductive System during Ovulation Affecting Fertility and Anticancer Activity

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Targeted drug delivery
Cancer treatment
Women's health
18

Marta Bergamo

Correlation between in vitro and in vivo release of radiolabeled antigen from PLGA microspheres using SPECT/CT imaging

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Other
19

Maya Kaduri

Cancer and the Nervous System: Using nanotechnology to target cancer associated neurons as a tool for treating breast cancer

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Cancer treatment
20

Michael Halim

Pharmacokinetic Variability of Long-circulating Nanomaterials: Insights into its Origins and Neglected Importance in Rodent Models

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Cancer treatment
21

Muneera Beach

Measuring the concentration of adeno-associated virus (AAV) with multi-angle dyanmic light scattering (MADLS) using the new zetasizer ULTRA

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Targeted drug delivery
22

Muneera Beach

Using Nanoparticle Tracking Analysis to Characterize Size and Concentration of Nanoparticles in Drug Delivery Systems

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Targeted drug delivery
23

Natalia Sannikova

Impact of Lipid Composition on Liposome Stability and Cannabinoid Drug Encapsulation Efficiency

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Microfluidics
Hydrophobic drug delivery
24

Noorjahan Aibani

Rethinking the Pertussis vaccine: Formulation of lipid nanoparticles with vaccine adjuvants to achieve enhanced immunity.

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Targeted drug delivery
25

Owen Daly

PRECLINICAL EVALUATION OF A MODIFIED MRNA FOR THE TREATMENT OF OTC DEFICIENCY

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Gene therapy
mRNA-LNP therapy
26

Pamela Schimmer

Large Animal Species for Evaluating Long-circulating Nanomaterial Toxicokinetics: Comparisons between Primates, Canines, and Rabbits

To be presented orally:
see program

Cancer treatment
27

Parth Patel

A subunit vaccine for bovine viral diarrhea: lipid-based formulation containing bovine viral diarrheas virus E2 protein in combination with adjuvants to improve immunogenicity

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Targeted drug delivery
28

Presley MacMillan

Liposome Imaging in Optically Cleared Tissues

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Targeted drug delivery
Cancer treatment
29

Richard Holland

PH-responsive endosomal release agents to enhance RNAi conjugate activity across multiple cell types and receptors

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Targeted drug delivery
30

Sarah Thomson

Design of lipid nanoparticle systems for brain gene therapy

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Targeted drug delivery
Gene therapy
31

Shahla Shojaei

A dynamic microphysiological model of placenta to study the effect of gold nanoparticles

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Targeted drug delivery
Diagnostics
Microfluidics
32

Shan Zou

Anti-Leukemia Effect by Stimulated-Macrophages in Co-Culture

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Cancer treatment
33

Songlin Yang

Development of A Suitable Surface by Coating with Antibody Modified Up-conversion Nanoparticles for Improvement of Cell Culture Performance

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Targeted drug delivery
Diagnostics
Microfluidics
34

Vinod Kumar

Coronavirus Outbreaks: Nanomedicine and Future Perspectives

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COVID-19
35

Yi-Nan Zhang

Nanoparticle size influences antigen retention and presentation in lymph node follicles for humoral immunity

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Targeted drug delivery
Vaccines
36

Youcef Chakib Hacene

Extraction of PEGylated nanoparticles by immunoprecipitation

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Analytical methodology
37

Agustín Picco

Poly(allylamine)-tripolyphosphate self-assemblies: Towards robust and biocompatible drug nanocarriers

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Targeted drug delivery
Controlled Release
Nanocarriers
38

Amir Khajavinia

Development of an extraction method for the quantification of docetaxel loaded in PLGA nanoparticles

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Targeted drug delivery
39

Amrita Dikpati

Physico-chemical characterization and biodegradation of a natural polymer and nanoparticles for applications in drug delivery.

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Targeted drug delivery
41

Assaf Zinger

Enhancing Inflammation Targeting Using Tunable Leukocyte-based Biomimetic Nanoparticles

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Targeted drug delivery
Microfluidics
Cancer treatment
42

Avi Schroeder

Barcoded Nanoparticles for Precision Cancer Medicine: Targeting pancreatic tumors with nanomedicine

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Targeted drug delivery
Diagnostics
Cancer treatment
44

Ben Ouyang

The dose threshold for nanoparticle tumour delivery

To be presented orally:
see program

Targeted drug delivery
Cancer treatment
45

Christina Tan

Time Course Study of Blood-pool and Liver Targeting Gold Nanoparticle Contrast Agents

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Nanoparticle Contrast Agents
46

Claudia Costa

Optimization of diazepam-loaded nanostructured lipid carriers (NLC) for nose-to-brain delivery using the quality by design (QbD) approach

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Targeted drug delivery
47

Daniel Gonzalez-Carter

Targeting nanoparticles to the brain by exploiting the blood–brain barrier impermeability to selectively label the brain endothelium

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Targeted drug delivery
48

Giovanna Cassone Salata

Bioresponsive Microemulsion for Prevention of Breast Cancer Development

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Cancer treatment
50

Iara Mara de Oliveira Viana

Complement cascade and the biological fate of liposomes in rodents

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Nano-bio interface
51

Jayesh Kulkarni

Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles

To be presented orally:
see program

Gene therapy
Microfluidics
52

Kieu Lam

Lipid nanoparticles enabling specific and functional extrahepatic delivery of nucleic acids

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Targeted drug delivery
53

Lokesh Narsineni

Development of peptide-modified gemini nanoplexes for non-viral gene delivery to the retina

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Gene therapy
54

Marilina Cathcarth

Comparing Antifouling Strategies on Silica Nanoparticles

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Targeted drug delivery
Protein corona
Antifouling Coatings
55

Marta Overchuk

Photodynamic Priming as a Means of Enhancing Nanomedicine Delivery and Overcoming Tumour Desmoplasia

To be presented orally:
see program

Targeted drug delivery
Cancer treatment
56

Maximilian Regenold

Drug loading levels affect in vitro release of vinorelbine from thermosensitive liposomes

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Targeted drug delivery
Cancer treatment
57

Miffy Hok Yan Cheng

A single metal multifunctional nanotexaphyrin as a radiotheranostics agent for cancer imaging and therapy

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Diagnostics
Cancer treatment
58

Moe Wehbe

Investigating the PK-PD relationship governing STING agonist nanoparticle efficacy upon systemic administration

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Cancer treatment
59

Philippe Grenier

Anti-polyethylene Glycol antibodies alter the protein corona on nanoparticles and their fate in vivo

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Overcoming biological barriers
60

Qurrat Ul Ain

Non-Viral delivery of CRISPR-Cas9 to the Skin aiming for in situ gene therapy for Autosomal recessive congenital Ichthyosis (ARCI)

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Gene therapy
62

Abdelaziz Saafane

Iron oxide nanoparticles: Question of nanosafety for nanomedicine applications

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Nanotoxicity
63

Stavroula Zagkou

Breaking Down Fat with Autophagy-Inducing Particles

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Targeted drug delivery
64

Suresh Gadde

Translational Nanomedicines for the Treatment of Triple Negative Breast Cancer

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Cancer treatment
65

Tiffany Carlaw

Successful Correction of a Pathogenic Mutation of the LPL gene Causing Lipoprotein Lipase Deficiency, Using a CRISPR/Cas9 Base Editing Therapeutic Approach

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Gene therapy
66

Valentina Francia

Exploring the Potential of a Personalized Corona in Lipid-based Nanoparticles for siRNA delivery

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Targeted drug delivery
Gene therapy
67

Siyue Yu

DEVELOPMENT OF IN VIVO MUTANT REPORTER MOUSE MODELS TO OPTIMIZE AND EVALUATE CRISPR/CAS9 THERAPEUTIC BASE EDITING

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Gene therapy
68

You Xu

Design of spray-dried TNF-α siRNA-loaded LPNs with high aerosol performance for treatment of COPD

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Targeted drug delivery
69

Alessandra Spada

Design and evaluation of albumin nanoparticles for the delivery of a beta-tubulin polymerization inhibitor

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Targeted drug delivery
70

Amir Gharib

Experimental treatment of breast cancer-bearing BALB/c mice by artemisinin and transferrin-loaded magnetic nanoliposomes

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Targeted drug delivery
71

Antonella Ibarguen Mejia

Development of an LC-MS/MS Method for the Characterization of Liposomes used in Drug Delivery

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Materials characterization
72

Barbara Malheiros

Phytantriol cubosomes flexibility and malleability evidenced by extrusion: a new method for drug encapsulation

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Targeted drug delivery
Nanoparticles for drug delivery
73

Carcia Carson

Engineering Nanotechnologies to Improve Immune Responses to Personalized Cancer Vaccines

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Cancer treatment
74

Courtney van Ballegooie

Microfluidic Synthesis of Protein-Gold Nanoparticle Hybrids: Potential for X-Ray triggered drug release

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Microfluidics
Cancer treatment
Triggered Release
75

Elisabet Rodriguez Llorian

Economic Evidence on Potentially Curative Gene Therapy Products: A Systematic Review

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Gene therapy
76

Erhunmwunsee Dalton Avan

Transferrin-Targeted Nanoparticle Delivery of ACGs: Release Kinetics and In-vitro Stability Studies

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Targeted drug delivery
Cancer treatment
77

Farahnaz Fathordoobady

Towards an understanding of optimum ultrasonication process time on size reduction of hempseed oil nanoemulsions

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Nanoemulsion for drug delivery
78

Heather Denroche

A nanomedicine approach for diabetes: targeting the NLRP3 inflammasome in tissue-resident macrophages

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Targeted drug delivery
79

Jerry Leung

Enhancing Platelets with Gene Therapy for More Effective Transfusions

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Gene therapy
80

Shrey Sindhwani

The entry of nanoparticles into solid tumours

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Cancer treatment
81

Letícia Ferragut Casotti

Factorial Study of Cubic Nanostructures Formulations and Structural Characterization

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Targeted drug delivery
82

Lih Jiin Juang

Coagulation factor XII contributes to hemostasis when activated by soil in wounds

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Natural nanoparticles & coagulation
83

Mahmoud Abdelkarim

Tuning Nanoparticles Size via Microchannel Geometry

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Microfluidics
84

Mandy Chan

Characterization of Small Extracellular Vesicles Produced by Human Mesenchymal Stromal Cells in an Improved Extracellular Vesicle-free Medium

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COVID-19
86

Maximiliano Agazzi

Self-Assembled Peptide Dendrigraft Supraparticles with Potential Application in pH/enzyme-Triggered Multistage Drug Release

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Targeted drug delivery
Cancer treatment
87

Mayra Lotierzo

Micellar to cubic transition in phytanthriol based nanoparticles

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Targeted drug delivery
89

Niloy Chatterjee

NANOMEDICINE-AN UNEXPLORED THERAPEUTIC REALM AGAINST COVID-19

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COVID-19
90

Santiago Esteban Herrera

Insulin-Delivery from Glucose-Responsive Polyamine-Salt Aggregates: Smart “Sense-and-Treat” Nanocarriers Made Easy

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Targeted drug delivery
91

Sara Abd El- Hafeez

Modulation of metformin hydrochloride water solubility via hydrophobic ion pairing approach to sustain its release from calcium alginate beads

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Controlled release
92

Sara Anselmo

Effect of cholesterol on the interaction between amphyphylic peptides and liposomes

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Other
93

Victor Passos Gibson

Survivin-targeted siRNA sensitizes retinoblastoma primary cells to Melphalan and Carboplatin

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Gene therapy
94

Wesley Walker

Bacteriopheophorbide nanoemulsions as photodynamic therapy agents

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Cancer treatment
95

Xin Ye

Development of HSD17B13 Targeting siRNA-GalNAc as a Potential Therapy for Fibrosis in NASH

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Targeted drug delivery
96

Zahra Eivazi Zadeh

Comparison of the Antibacterial Effect of Tio2 and Ag Nanoparticles Prepared by Laser Ablation and Sol-Gel on Burn Related Bacteria

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Antibacterial agents
97

Igor M. Paiva

Polymeric micellesofa novel inhibitor of DNA repair enzyme, polynucleotide kinase/phosphatase(PNKP), for targeted treatment ofnon-small cell lung canceras monotherapy or in combination with Irinotecan

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98

Nashmia Zia

Development of Polymer Capped Sorafenib Loaded Gold Nanoparticles for Treatment of FLT3 Positive Acute Myeloid Leukemia

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Targeted drug delivery, Cancer treatment
99

Nashmia Zia

Design and evaluation of albumin nanoparticles for the delivery of a beta-tubulin polymerization inhibitor

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Diagnostics, SPECT nano-radiopharmaceutical